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KMID : 0359420230410040233
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Korean Journal of Sports Medicine
2023 Volume.41 No. 4 p.233 ~ p.240
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Association between Estimated Cardiorespiratory Fitness and Insulin Resistance in Korean Adults: Results from the Korea National Health and Nutrition Survey 2019?2021
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Han Yun-Min
Kim Yeon-Soo
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Abstract
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Purpose: The purpose of this study was to investigate the association between estimated cardiorespiratory fitness (eCRF) and insulin resistance in Korean adults, and to compare this association through sex and age-specific analyses.
Methods: A total of 13,405 adults aged 19 years and older (male, 5,869; female, 7,536) were analyzed using data from the Korea National Health and Nutrition Survey (KNHANES) for the years 2019 to 2021. eCRF was analyzed by dividing it into quartiles using the estimation equation based on age, sex, body mass index, waist circumference, smoking status, resting heart rate, and self-reported physical activity level. Insulin resistance was measured to calculate the HOMA-IR. Logistic regression was used to predict the odds ratio (OR) and 95% confidence interval (CI) of the relationship between the two variables, with adjustment for potential confounders.
Results: The results showed a stronger association between fitness level and insulin resistance. Based on the first quartile (reference group), the lower the cardiorespiratory fitness level, the higher the OR. In male subjects, the lowest quartile had an OR of insulin resistance 17.65 (95% CI, 13.76?22.64). For female subjects, the lowest quartile had an OR of insulin resistance 7.96 (95% CI, 6.37?9.94). These results indicate a strong inverse relationship between cardiorespiratory fitness and insulin resistance and younger groups exhibited significantly higher ORs in age-specific ORs.
Conclusion: The analysis results demonstrated that increasing cardiorespiratory fitness levels can significantly impact insulin sensitivity and reduce insulin resistance risk.
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KEYWORD
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Cardiorespiratory fitness, Insulin resistance, Metabolism
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